The maternal prepregnancy body mass index and the risk of attention deficit hyperactivity disorder among children and adolescents: a systematic review and meta-analysis / 소아과

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) symptoms have a major impact on individuals, families, and society. Therefore identification risk factors of ADHD are a public health priority. PURPOSE: This is meta-analysis evaluated the association between maternal prepregnancy body mass index and the risk of ADHD among the resulting offspring. METHODS: The search identified studies published through December 2018 in the PubMed, Web of Science, and Scopus databases. The odds ratios (ORs) or hazard ratios (HRs) with 95% confidence intervals (CI) extracted from eligible studies were used as the common measure of association among studies. RESULTS: A significant association was found between overweight women and the risk of ADHD among children with the pooled HR and OR estimates (HR, 1.27 and 95% CI, 1.17–1.37; OR, 1.28 and 95% CI, 1.15–1.40, respectively). This association was significant between obese women and the risk of ADHD among children and adolescents with the pooled estimates of HR and OR (HR, 1.65 and 95% CI, 1.55–1.76; OR, 1.42 and 95% CI, 1.23–1.61). CONCLUSION: The current epidemiological studies present sufficient evidence that prepregnancy overweight and obesity are significantly associated with an increased risk of ADHD among children and adolescents. These findings provide a new approach to preventing ADHD by controlling weight gain in the prenatal period, which should be considered by policymakers.

Awareness of pregnant women about folic acid supplementation in Iran

The purpose of this study was to determine the level of knowledge of folic acid supplementation amongst Iranian pregnant women. We selected 322 women through simple randomized method in a cross section study. Data was gathered on the base of questionnaire and interview. Statistical analysis was performed using SPSS software. The value of p<0.05 was considered as significant level. The obtained information revealed that 7.8% with high level of knowledge, 43.8% with intermediate level, 30.4% with low level knowledge, and 18% with no knowledge. Hospitals and health centers are two major sources for promoting popular awareness about folic acid. There is a significant relationship between the knowledge, education, employment, time of prenatal care beginning, age, gravidity, and sources of health information. The number of women with high level of knowledge was more among those with lower parity, higher level of education, employment, young age and looking for health information. Awareness of folic acid is low among Iranian women. The different strategies are required to elevate the knowledge about folic acid among the women in reproductive age and provide them with some information about the benefits of this supplement